The Key Points
Question Is therapeutic hypothermia associated with better survival outcomes for patients with in-hospital cardiac arrest?
Findings In this cohort study using a US national registry, survival outcomes were compared for 26 183 patients who were treated vs not treated with therapeutic hypothermia after surviving an in-hospital cardiac arrest. Compared with untreated patients, those treated with therapeutic hypothermia had significantly lower rates of in-hospital survival (29.2% vs 27.4%, respectively), as well as lower rates of survival to discharge with favorable neurological status.
Meaning Therapeutic hypothermia was not associated with improved survival or better neurological outcomes and was potentially harmful. Current use of therapeutic hypothermia for in-hospital cardiac arrest may warrant reconsideration